Sepsis risk persists up to 12 years after hospital discharge: 3 studies

According to new data published in Journal of the American Heart Association.

A team of researchers at the Mayo Clinic in Rochester, Minnesota, used a national database of administrative claims to identify more than 800,000 patients who had sepsis during their hospital stay and survived between 2009 and 2019. who were hospitalized for it or developed it during hospitalization, as well as subsequent readmissions, death and cardiovascular consequences during the follow-up period from 2009 to 2021.

Three conclusions:

1. Compared with patients without sepsis at the time of hospitalization, patients with this disease had a 38% higher risk of rehospitalization for all causes, and a 43% higher risk of rehospitalization for cardiovascular reasons within 12 years.

2. The risk of developing heart failure after discharge was 51% higher among patients who had sepsis during hospitalization compared with those who did not have it.

3. The risk of death after discharge was 27% higher among people who had sepsis during hospitalization.

“Our results indicate that after hospitalization for sepsis, close follow-up is important, and it may be beneficial to provide closely monitored CVD prevention therapy.” – Jacob Jenzer, MD, lead author of the study and assistant professor of cardiovascular medicine at the Mayo Clinic. , according to a February 1 press release. “Professionals should be aware that people with a history of sepsis are at very high risk of cardiovascular events, and that it may be necessary to advise them to increase the intensity of cardiovascular disease prevention.”